Diflubenzuron was the first chitin synthesis inhibitor developed and remains widely used for mosquito larvae, gypsy moth, forest pests, and livestock fly control. It prevents insect larvae from successfully molting by blocking chitin formation in the new exoskeleton.
Mosquito larvae, gypsy moth caterpillars, forest defoliators, fly larvae (in manure and livestock settings), leafminers, whitefly nymphs, fungus gnats. Primarily effective against larval/immature stages - does NOT kill adult insects.
Products and Brand Names
Dimilin (the original brand, Chemtura/LANXESS), Micromite (ornamental), Adept (livestock), various generic diflubenzuron products. Used extensively in government mosquito abatement and forest pest management programs.
Safety and Precautions
Low mammalian toxicity. Chitin synthesis inhibitors are inherently selective because mammals do not produce chitin. However, diflubenzuron is toxic to aquatic crustaceans (shrimp, crabs, lobsters) because they also produce chitin. Use extreme caution near marine and freshwater environments.
Aquatic invertebrates: Diflubenzuron is highly toxic to crustaceans, including commercially important species. Application near estuaries, tidal areas, or shellfish beds is restricted. Always observe buffer zones on the label.
Pro Tips
Mosquito control: Diflubenzuron is applied to standing water where mosquito larvae develop. It prevents larvae from molting to the pupal stage. Very effective in large-scale mosquito abatement programs. Applied by ground or aerial application to wetlands, ditches, and flood pools.
Selectivity advantage: Unlike broad-spectrum larvicides, diflubenzuron primarily affects arthropods that must molt. Fish, birds, mammals, and adult insects are not directly affected. This makes it useful in sensitive habitats where fish and amphibian populations must be protected.
Gypsy moth programs: USDA and state agencies use diflubenzuron aerially to suppress gypsy moth outbreaks in forests. It is applied when caterpillars are in early instars (small) for maximum effectiveness.
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Follow the product label. Keep pets out of treated areas until completely dried (2โ4 hours for sprays). Once dry, treated surfaces pose minimal risk to dogs and cats.
Q: Can I use diflubenzuron indoors?
Check the specific product label โ formulations vary. Baits and dusts often have indoor labeling; concentrates and granulars are typically outdoor.
Q: How long does diflubenzuron last after application?
Residual varies by formulation, surface type, weather, and UV exposure. Indoor applications last longer than outdoor. Check the product label for re-application intervals.
Q: What should I do if exposed?
Remove contaminated clothing, wash skin with soap and water. For eye contact, rinse 15โ20 minutes. For ingestion or severe symptoms, call Poison Control (1-800-222-1222). Have the product label available.
๐ Safety Data Sheet (SDS)
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Diflubenzuron โ Safety Data Sheet
View the official SDS document for this product directly on the CDMS label database.
Did you know? Diflubenzuron was developed by Philips-Duphar in the Netherlands in the 1970s and was the worlds first commercial chitin synthesis inhibitor. It proved that targeting chitin - a structural molecule found only in arthropods and fungi - was a viable and selective approach to pest control.
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Reviewed by Derek GiordanoContent reviewed by a licensed pest management professional. Last reviewed: April 2026.