Active Ingredient Profile

Etofenprox

Pyrethroid-like Ether Insecticide

Etofenprox acts like a pyrethroid but is chemically an ether, not an ester. This distinction matters because it gives etofenprox significantly lower fish toxicity than true pyrethroids while maintaining similar insecticidal activity. Used in mosquito control, agriculture, and some consumer products.

🧪
Classification
Pyrethroid-like Ether Insecticide
Signal Word
Caution
Mode of Action
Sodium channel modulator (similar to pyrethroids): disrupts nerve signal transmission causing paralysis
โš–๏ธ Educational use only. Always read and follow the full product label โ€” the label is the law under FIFRA. Full disclaimer โ†’ | โš—๏ธ Mixing Calculator โ†’

Target Pests

Mosquitoes (adult and larval), rice pests, vegetable pests, stored product pests, flies, gnats. Broad-spectrum contact and ingestion insecticide effective against most flying and crawling insects.

Products and Brand Names

Trebon (Mitsui Chemicals - the original brand), Zenivex (mosquito adulticide for public health programs), Vectobac plus etofenprox combinations, various agricultural formulations. Limited consumer products in the US.

Safety and Precautions

Lower mammalian toxicity than most pyrethroids. The key advantage is dramatically reduced fish and aquatic toxicity compared to true pyrethroids like bifenthrin or permethrin. This makes it preferred for mosquito control programs near waterways.

Aquatic safety: Etofenprox is 100-1000x less toxic to fish than bifenthrin or permethrin. This is why mosquito abatement districts increasingly prefer it for applications near rivers, lakes, and estuaries.

Pro Tips

Why not a pyrethroid: Despite acting exactly like a pyrethroid at the nerve level, etofenprox has a different chemical structure (ether vs ester bond). This structural difference is why fish can metabolize and detoxify it much more efficiently than true pyrethroids.

Mosquito control: Used as an adulticide in ULV (ultra-low volume) truck-mounted and aerial spray programs. Provides excellent mosquito knockdown with a better environmental profile than permethrin or sumithrin in aquatic-adjacent areas.

Cross-resistance: Because etofenprox targets the same sodium channel as pyrethroids, insects with pyrethroid resistance (kdr mutations) may also show reduced susceptibility to etofenprox. This limits its usefulness in areas with established pyrethroid resistance.

๐Ÿ› Pests This Treats โ€” Learn More

Click any pest to view its full identification guide, biology, and treatment options.

๐Ÿ› Flies โ†’ ๐Ÿ› Gnats โ†’ ๐Ÿ› Mosquito โ†’ ๐Ÿ› Scales โ†’ ๐Ÿ› Ticks โ†’

๐ŸŒฟ Environmental & Ecological Impact

๐Ÿ Bees / PollinatorsMODERATE
๐ŸŸ Fish / Aquatic LifeHIGH
๐Ÿฆ BirdsLOW
๐Ÿ• Mammals / PetsLOW
๐Ÿฆ Aquatic InvertebratesHIGH
๐Ÿ’ก Lower aquatic toxicity than most pyrethroids but still significant. Reduced bee risk.
Example
0.5 oz
per gallon
โš—๏ธ Mixing Calculator
Enter your sprayer size and target rate โ€” get the exact amount to pour. Backpack, hand sprayer, hose-end, or skid unit.
Open Calculator โ†’

โ“ Frequently Asked Questions

Q: Is etofenprox safe for pets?
Follow the product label. Keep pets out of treated areas until completely dried (2โ€“4 hours for sprays). Once dry, treated surfaces pose minimal risk to dogs and cats.
Q: Can I use etofenprox indoors?
Check the specific product label โ€” formulations vary. Baits and dusts often have indoor labeling; concentrates and granulars are typically outdoor.
Q: How long does etofenprox last after application?
Residual varies by formulation, surface type, weather, and UV exposure. Indoor applications last longer than outdoor. Check the product label for re-application intervals.
Q: What should I do if exposed?
Remove contaminated clothing, wash skin with soap and water. For eye contact, rinse 15โ€“20 minutes. For ingestion or severe symptoms, call Poison Control (1-800-222-1222). Have the product label available.

๐Ÿ“‹ Safety Data Sheet (SDS)

๐Ÿ“‹

Etofenprox โ€” Safety Data Sheet

View the official SDS document for this product directly on the CDMS label database.

Etofenprox Safety Data Sheet page 1
๐Ÿ“„ Etofenprox โ€” Safety Data Sheet ยท View the complete SDS document above or download below
Did you know? Etofenprox was developed in Japan by Mitsui Chemicals and is one of the most widely used insecticides in Asian rice production. Its low fish toxicity makes it ideal for rice paddies where fish are often co-cultivated with the rice crop.
🔮
Reviewed by Derek GiordanoContent reviewed by a licensed pest management professional. Last reviewed: April 2026.
๐Ÿ“š Sources: EPA Pesticide Labels ยท NPIC Pesticide Info
Published: Jan 1, 2025 ยท Updated: Apr 7, 2026