The label is the law. Rates and restrictions below are taken from the product labels listed under Sources. Your product's own label governs; read it before you mix or apply. Mixing calculator · Disclaimer
- Active ingredient
- Mancozeb
- Chemical class
- A coordination product of zinc ion and manganese ethylene bisdithiocarbamate; FRAC Group M03, dithiocarbamates and relatives with multi-site activity.[1][2]
- Mode of action
- FRAC Group M03: Multi-site contact activity: dithiocarbamates and relatives[2][1]
- Signal word
- Dithane F-45 Fungicide (also sold as Dithane F-45 Rainshield): none required[1]
Who can use Dithane F-45
This is a professional product. The turf directions bar residential lawns and athletic fields, and the ornamental section says it is intended only for professional applicators and not for residential greenhouses.[1]
The label also carries a California notice that it contains mancozeb and ETU, which the state lists as causing cancer, with ETU also listed for birth defects or reproductive harm.[1]
Why M03 matters for resistance
Group M fungicides act on many sites in the fungus at once. The label still advises rotating or tank-mixing it with fungicides from other groups that control the same diseases.[2][1]
Where it is used
It is a protectant, so timing matters. Start at the first sign of disease, when disease is reported nearby, or when the weather favors it, and keep to the spray schedule.[1]
Shake the jug well before use: twist and invert it 5 to 10 times so the contents fully resuspend. Keep it from freezing and from overheating in storage.[1]
For hand sprayers, premix it as a slurry with an equal amount of water, then add it to a half-filled tank. Put it in before any other product.[1]
On turf, start at spring green-up or first disease and repeat every 7 to 14 days. Use the top rate with at least 10 days between sprays when conditions favor disease.[1]
Products and registrations
| Product | Registrant | EPA Reg. No. | Active % | Formulation | Signal word |
|---|---|---|---|---|---|
| Dithane F-45 Fungicide (also sold as Dithane F-45 Rainshield)[1] | UPL NA, Inc. | 70506-654 | 37.0% | flowable liquid | none |
Label rates
| Product | Use | Pests | Rate |
|---|---|---|---|
| Dithane F-45 Fungicide (also sold as Dithane F-45 Rainshield) | Golf courses, sod farms, and industrial or municipal turf (not residential lawns) | Brown patch, dollar spot, rust, red thread, melting-out, pythium blight, fusarium snow mold, gray leaf spot, slime mold, algae | 6.4–12.8 fl oz product per 1,000 sq ft[1] 6.4 fl oz for melting-out, rust and brown patch; 9.6 to 12.8 fl oz for dollar spot and snow mold; 12.8 fl oz for pythium blight and gray leaf spot. Repeat every 7 to 14 days, at least 10 days apart. |
| Dithane F-45 Fungicide (also sold as Dithane F-45 Rainshield) | Outdoor and greenhouse ornamentals, including roses, azaleas, camellias, dogwood and crabapple | Black spot, rusts, leaf spots, botrytis blight, petal blight, anthracnose, cedar-apple rust and scab | 1.2 qt product per 100 gallons of dilute spray[1] Spray every 7 to 10 days through the season once plants leaf out or disease first shows. No more than 24 qt per acre per year. |
Safety and environmental hazards
People
Dithane F-45 carries no signal word. Handlers wear long sleeves, long pants, waterproof chemical-resistant gloves, shoes and socks, and farm workers stay out for 24 hours after treatment.[1]
Pets
At golf courses and municipal lawns, unprotected people must stay out of treated areas until sprays have dried. Treated seed must be kept away from children, pets and livestock.[1]
Bees and pollinators
The label has no bee or pollinator warning. Its environmental hazard statement concerns aquatic life.[1]
Fish and water
Toxic to aquatic organisms, and drift or runoff can harm them in nearby areas. Don't apply directly to water or where surface water is present.[1]
Common questions
- Can I spray mancozeb on my home lawn?
- Not with Dithane F-45. Its turf section is for golf courses, sod farms and industrial or municipal turf, and it says not to apply to residential turf.[1]
- Does mancozeb cure black spot on roses?
- It prevents rather than cures. The label lists black spot, rust and cercospora leaf spot on roses, sprayed every 7 to 10 days from leaf-out or first symptoms.[1]
- Is mancozeb systemic?
- No. The label calls it a protectant fungicide, and FRAC puts it among the multi-site contact fungicides.[1][2]
Sources
- U.S. EPA Pesticide Product Label System, “Dithane F-45 Fungicide label, EPA Reg. No. 70506-654 (EPA-stamped, Feb. 29, 2024).” www3.epa.gov/pesticides/chem_search/ppls/062719-00396-20240229.pdf (accessed 2026-10-06). EPA's site files this label under the product's earlier registration number, 62719-396.
- Fungicide Resistance Action Committee, “FRAC Code List 2025.” www.frac.info/media/ljsi3qrv/frac-code-list-2025.pdf (accessed 2026-10-06). Mancozeb is listed under dithiocarbamates and relatives, FRAC code M03 (multi-site contact activity).