Igr mechanism of action diagram

How igr works — illustrated mechanism of action · PestControlBasics.com

OTC/DIY CAUTION

Pyriproxyfen — Nylar, Martin's IGR, Distance

Active ingredient: pyriproxyfen  ·  Residual: 120–150 days (indoor)

⚠️ Don't buy duplicates. All brands listed contain the same active ingredient. Buying two different brands is buying the same pesticide twice.
⚖️ Educational use only. Always read and follow the full product label — the label is the law under FIFRA. Full disclaimer → | ⚗️ Mixing Calculator →

🏷️ Brand Names — Same Active Ingredient

Nylar — Zoëcon/MGK — professional concentrate
Distance IGR — Valent BioSciences — professional
Martin's IGR — consumer generic — both methoprene and pyriproxyfen versions — check label

🎯 What It Kills

✓ Fleas✓ Cockroaches✓ Whiteflies✓ Scale✓ Mosquitoes✓ Ants (fire ants)

⚙️ How It Works

Pyriproxyfen is a juvenile hormone analog IGR similar to methoprene but with somewhat different spectrum. Particularly effective against whiteflies in greenhouse settings and as a flea control IGR. Note: Martin's IGR is sold in both methoprene and pyriproxyfen versions — check the active ingredient on your specific bottle.

⚗️ Mixing & Application

Nylar 0.5%: 1 oz per gallon for indoor carpet treatment. For outdoor use: 2 oz per gallon. Combined with adulticide for complete flea control.
Example
0.5 oz
per gallon
⚗️ Mixing Calculator
Enter your sprayer size and target rate — get the exact amount to pour. Backpack, hand sprayer, hose-end, or skid unit.
Open Calculator →

⚠️ Safety

  • ⚠ Not an adulticide — must combine with a kill product
  • ⚠ Check which active ingredient is in Martin's IGR — both versions sold under same brand
  • ⚠ Very low mammalian toxicity — one of the safest pesticide classes

🐛 Pests This Treats — Learn More

Click any pest to view its full identification guide, biology, and treatment options.

🐛 Ants → 🐛 Cockroaches → 🐛 Fire Ant → 🐛 Fleas → 🐛 Flies → 🐛 Mosquito → 🐛 Scales → 🐛 Ticks → 🐛 Whiteflies →

🌿 Environmental & Ecological Impact

🐝 Bees / PollinatorsLOW
🐟 Fish / Aquatic LifeLOW
🐦 BirdsLOW
🐕 Mammals / PetsLOW
🦐 Aquatic InvertebratesMODERATE
💡 Highly selective IGR. Very low vertebrate toxicity. Can affect aquatic insect larvae at high concentrations.

⏱️ Residual & Re-entry Timeline

🔹
Apply
Follow label mixing and application rates
🔸
Re-entry: 2–4 hours
Keep people and pets out of treated area
🟢
Effective period: 120–150 days
Active residual — killing or repelling target pests
🔄
Reapply
Re-treat when pest activity returns or residual expires

🔄 Alternatives & Related Products

Same chemical class or different approaches to the same pests.

🔄
Methoprene
Same class: IGR
↔️
Pyrethrin
Different approach: Botanical Pyrethrin
↔️
Boric Acid
Different approach: Inorganic

❓ Frequently Asked Questions

Q: Is pyriproxyfen safe for pets?
Follow the product label. Keep pets out of treated areas until completely dried (2–4 hours for sprays). Once dry, treated surfaces pose minimal risk to dogs and cats.
Q: Can I use pyriproxyfen indoors?
Check the specific product label — formulations vary. Baits and dusts often have indoor labeling; concentrates and granulars are typically outdoor.
Q: How long does pyriproxyfen last after application?
Residual varies by formulation, surface type, weather, and UV exposure. Indoor applications last longer than outdoor. Check the product label for re-application intervals.
Q: What should I do if exposed?
Remove contaminated clothing, wash skin with soap and water. For eye contact, rinse 15–20 minutes. For ingestion or severe symptoms, call Poison Control (1-800-222-1222). Have the product label available.

📋 Safety Data Sheet (SDS)

📋

Nyguard IGR — Safety Data Sheet

View the official SDS document for this product directly on the CDMS label database.

Nyguard IGR Safety Data Sheet page 1
📄 Nyguard IGR — Safety Data Sheet · View the complete SDS document above or download below
📚 Sources: EPA Pesticide Labels · NPIC Pesticide Info
Published: Jan 1, 2025 · Updated: Apr 7, 2026
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Reviewed by Derek GiordanoContent reviewed by a licensed pest management professional and cross-referenced against EPA, university extension, and manufacturer technical data. Last reviewed: April 2026.