The label is the law. Read your product's label before you mix or apply; the rates here come from the labels listed under Sources.
- Active ingredient
- Bacillus subtilis strain QST 713
- Chemical class
- Microbial biofungicide; FRAC Group BM02 (biologicals with multiple modes of action).[2][1]
- Mode of action
- FRAC Group BM02: Biologicals with multiple modes of action: microbial strains[2][1]
- Signal word
- Serenade Garden Disease Control (Serenade ASO): Caution[1]
Control versus suppression
The label separates diseases it controls, such as powdery mildew, black spot of rose, gray mold and brown patch and dollar spot on lawns, from ones it only suppresses, such as early blight, late blight, downy mildew, bacterial spot, fire blight and scab. For suppressed diseases, expect partial control.[1]
Where it is used
It works preventively: treat before foliar disease develops or at the first sign of infection, and repeat every 7 days or as needed, more often in humid or rainy weather.[1]
It can be used any time of day, in full sun and high heat, without burning foliage, and up to and on the day of harvest.[1]
Heavy rain or irrigation soon after spraying may mean retreating. Don't let mixed spray stand overnight in hand sprayers.[1]
Products and registrations
| Product | Registrant | EPA Reg. No. | Active % | Formulation | Signal word |
|---|---|---|---|---|---|
| Serenade Garden Disease Control (Serenade ASO)[1] | Bayer CropScience LP | 264-1152 | 1.34% | aqueous suspension biofungicide | Caution |
Label rates
| Product | Use | Pests | Rate |
|---|---|---|---|
| Serenade Garden Disease Control (Serenade ASO) | Home vegetables, fruits, nuts, roses, flowers, trees and shrubs | Powdery mildew, black spot of rose, gray mold, leaf spots, rust; suppression of early and late blight, downy mildew, bacterial spot, fire blight and scab | 2–4 fl oz product per gallon of water[1] 2 to 4 fl oz (4 to 8 tablespoons) per gallon, sprayed to run-off on both sides of leaves. On lawns, 2 to 8 fl oz per gallon applied at 1 gallon per 1,000 sq ft. |
How to apply it, step by step
1. Protective gear
- The home-use sublabel lists no specific gear: it is harmful if inhaled, so avoid breathing the spray mist, and wash contaminated clothing before wearing it again.[1]
2. Before you spray
- It is a preventive biofungicide for roses, vegetables, fruits, nuts, flowers, houseplants, trees, shrubs and lawns: start before leaf disease appears or at the first sign of it.[1]
- Don't let spray drift off the plants you're treating; it can go on any time of day, in full sun and heat, without burning leaves.[1]
- Spray in calm weather when no rain is forecast for 24 hours, and keep it out of storm drains and gutters.[1]
3. Mixing
- Shake well, then mix with water only: 2 to 4 fl oz (¼ to ½ cup) per gallon for fruits, vegetables, nuts, flowers, trees and shrubs, and 2 to 8 fl oz per gallon for lawns.[1]
- In a hand sprayer or trigger bottle, mix thoroughly, keep the mix agitated while spraying, and don't let it stand overnight. A hose-end sprayer dilutes it automatically at the dial setting.[1]
4. Applying
- Spray plants to runoff, covering the tops and bottoms of the leaves.[1]
- On lawns, apply 1 gallon of the mix per 1,000 sq ft.[1]
- Repeat every 7 days or as needed, and more often when high humidity or heavy rain favors disease.[1]
5. After you spray
- It can be used up to and on the day of harvest.[1]
- Rinse the sprayer over the treated area so the rinse water doesn't run into drains.[1]
First aid
- If inhaled, move the person to fresh air, call 911 if they aren't breathing, and call a poison control center or doctor.[1]
- The label's 24-hour line for medical and transportation emergencies is 1-800-334-7577.[1]
Storage, spills and disposal
- Store it in its original container, closed, at room temperature, out of children's reach, and away from water, food and feed.[1]
- Put an empty container in the trash or recycling; for a partly full one, call your local solid waste agency, and never pour product down a drain.[1]
From the safety data sheet
- The product is a brown suspension with a sweet, earthy odor containing 1.34 percent Bacillus subtilis strain QST 713.[3]
- The SDS rates it not hazardous under the OSHA hazard communication standard, though it notes that microorganisms may cause sensitizing (allergic) reactions.[3]
- After skin contact, take off contaminated clothing and wash the skin with plenty of water for at least 15 minutes; if it is inhaled, move to fresh air.[3]
- Soak up spills with an inert absorbent such as sand or sawdust, collect it in a labeled, tightly closed container, and clean contaminated surfaces thoroughly.[3]
- Wash your hands with soap and water after handling it and before eating, drinking or using the toilet.[3]
Safety and environmental hazards
People
Signal word CAUTION: harmful if inhaled, so avoid breathing spray mist. Repeated exposure to high concentrations of microbial proteins can cause allergic sensitization.[1]
Pets
The label's hazard statement for people and domestic animals is inhalation; avoid breathing spray mist and wash contaminated clothing.[1]
Bees and pollinators
The home-use label carries no bee hazard statement.[1]
Fish and water
Keep it out of storm drains, ditches, gutters and surface water, and apply in calm weather with no rain forecast for 24 hours.[1]
Common questions
- Is Serenade organic?
- The label includes statements that it can be used for organic production and organic lawn care.[1]
- Can I spray Serenade the day I pick tomatoes?
- Yes. The label says it can be applied up to and on the day of harvest.[1]
- Does Serenade cure powdery mildew?
- It is a preventive product; the label says to apply before disease develops or at the first sign, then every 7 days.[1]
Sources
- U.S. EPA Pesticide Product Label System, “Serenade ASO (Serenade Garden Disease Control) label, EPA Reg. No. 264-1152 (EPA-stamped, Feb. 12, 2025).” www3.epa.gov/pesticides/chem_search/ppls/000264-01152-20250212.pdf (accessed 2026-10-06)
- Fungicide Resistance Action Committee, “FRAC Code List 2025.” www.frac.info/media/ljsi3qrv/frac-code-list-2025.pdf (accessed 2026-10-06)
- Bayer CropScience, “SERENADE ASO Safety Data Sheet (Bayer CropScience, version 1.0 USA, revised March 26, 2015; EPA Reg. No. 264-1152, the label on this page; copy hosted by Greenbook).” assets.greenbook.net/M115941.pdf (accessed 2026-10-17)