Active ingredient profile

Isaria fumosorosea

Insect-pathogenic fungus. IRAC puts fungal agents in Group UNF and lists another strain of this species, Apopka 97, under its older name Paecilomyces fumosoroseus.[2][1]

Isaria fumosorosea is a fungus that infects insects and mites. NoFly WP holds live spores of strain FE 9901 at 18% of the powder. Infected pests usually die in 3 to 7 days, and a population drop shows up 7 to 10 days after the first spray.[1]

The label is the law. Rates and restrictions below are taken from the product labels listed under Sources. Your product's own label governs; read it before you mix or apply. Mixing calculator · Disclaimer

Active ingredient
Isaria fumosorosea strain FE 9901
Chemical class
Insect-pathogenic fungus. IRAC puts fungal agents in Group UNF and lists another strain of this species, Apopka 97, under its older name Paecilomyces fumosoroseus.[2][1]
Mode of action
IRAC Group UNF: Fungal agents of unknown or uncertain mode of action[2]
Signal word
NoFly WP (master label with a home and garden sublabel): Caution[1]

Control on one sublabel, suppression on another

The home and garden sublabel says NoFly is effective against whitefly, aphids, thrips, mites, beetles, psyllids, mealybugs and fungus gnats. The commercial sublabel lists the same plant pests for suppression only.[1]

In commercial poultry houses and livestock barns, the label targets litter beetles (darkling, hide and carrion), northern fowl mites, red poultry mites, moths and gnats at 1 to 3 oz per 12 gallons of water.[1]

Where it is used

Start at the first sign of pest eggs, larvae or nymphs, before numbers build. Repeat 2 or 3 times at 15-day intervals, or every 5 to 8 days if pressure is heavy.[1]

The spores are alive. Keep the bag refrigerated at about 46°F, bring it to room temperature before use, and protect it from heat above 86°F.[1]

Use it when soil temperature is between 39°F and 86°F. Commercial users are told to spray in late afternoon or evening, when humidity is high.[1]

Don't spray fungicides with it or within a week of it. Test on a few leaves first and check back in 2 to 4 days for plant injury.[1]

Products and registrations

ProductRegistrantEPA Reg. No.Active %FormulationSignal word
NoFly WP (master label with a home and garden sublabel)[1]FuturEco Bioscience, S.A.88664-118.0%wettable powder of live fungal sporesCaution

Label rates

ProductUsePestsRate
NoFly WP (master label with a home and garden sublabel)Home fruit and vegetable plants, flowers, roses, houseplants, trees, shrubs and lawnsWhitefly, aphids, thrips, mites, beetles, psyllids, mealybugs and fungus gnats2–4 tsp product per gallon of water[1]
Spray leaves, stems and new shoots to run-off, or soak the soil at the plant's base. On lawns, apply 1 gallon of mix per 200 square feet. Use the higher rate for heavy pest pressure.
NoFly WP (master label with a home and garden sublabel)Greenhouse plants, nursery crops, turf and outdoor food cropsSuppression of whiteflies, aphids, thrips, mites, mealybugs, leafhoppers, weevils, beetles and others2–8 oz product per 11,000 sq ft[1]
That's 1/2 to 2 pounds per acre, mixed at no less than 16 oz per 100 gallons of water.

Safety and environmental hazards

People

Signal word CAUTION: harmful if swallowed, inhaled or absorbed through skin. Prolonged or repeated skin contact may cause allergic reactions, so home users wear protective eyewear and waterproof gloves.[1]

Pets

The hazard statement covers people and domestic animals. In poultry and livestock housing, the label bars spraying where children, pets or animals can reach it or lick it, and treated surfaces must dry before animals return.[1]

Bees and pollinators

The label carries no bee or pollinator hazard statement.[1]

Fish and water

Don't apply it directly to water or let it run into storm drains, ditches, gutters or surface water. Spray in calm weather with no rain expected for 24 hours.[1]

Common questions

How fast does NoFly WP work?
An infected insect or mite typically dies in 3 to 7 days, and you should see fewer pests 7 to 10 days after the first spray.[1]
Can I spray it right before harvest?
Yes. The label sets a zero-day pre-harvest interval, so it can go on up to and on the day of harvest.[1]
Is NoFly WP organic?
Its optional label statements include use in organic gardening and organic lawn care on the home sublabel.[1]

Sources

  1. U.S. EPA Pesticide Product Label System, “NoFly WP master label label, EPA Reg. No. 88664-1 (EPA-stamped, Mar. 15, 2022).” www3.epa.gov/pesticides/chem_search/ppls/088664-00001-20220315.pdf (accessed 2026-10-06)
  2. Insecticide Resistance Action Committee, “IRAC Mode of Action Classification Scheme, Version 11.5 (Feb. 2026).” irac-online.org/documents/moa-classification/ (accessed 2026-10-06)

Updated 2026-10-06. Built from sourced records; every rate traces to a product label. Spot an error? Tell us.