Pyrethroid mechanism of action diagram

How pyrethroid works β€” illustrated mechanism of action Β· PestControlBasics.com

πŸ§ͺ Active Ingredient Profile

Deltamethrin Insecticide Profile

Synthetic Pyrethroid (Type II)

Deltamethrin is one of the most potent synthetic pyrethroids β€” effective at extremely low concentrations. Delta Dust (0.05% deltamethrin) is the most widely used professional insecticidal dust in North America.

πŸ§ͺ
CAS Number
52918-63-5
Mode of Action
Binds to voltage-gated sodium channels causing prolonged nerve activation and paralysis β€” among the most potent pyrethroids on a per-weight basis
βš–οΈ Educational use only. Always read and follow the full product label β€” the label is the law under FIFRA. Full disclaimer β†’ | βš—οΈ Mixing Calculator β†’

πŸ“‹ Key Facts at a Glance

Chemical Class
Synthetic Pyrethroid
Signal Word
Caution
Residual Duration
6+ months as dust; 30-60 days as liquid
Primary Products
Delta Dust (dust), Suspend SC (liquid), Suspend Polyzone
Key Application
Wall void dusting, attic treatments, outdoor perimeter
Aquatic Toxicity
Very high β€” keep away from water
Moisture Stability
Delta Dust is moisture-resistant β€” maintains efficacy in damp areas

🎯 Primary Uses in Pest Control

Deltamethrin liquid (Suspend SC) is used for perimeter treatments, indoor crack and crevice, and surface sprays. Delta Dust is used primarily for: wall void treatments (via drill holes or outlet plates), attic treatments for overwintering insects, crawl space treatments, and harborage areas where liquid application is impractical. Delta Dust is particularly valued for treating wall voids that harbored yellow jackets, stink bugs, or roaches.

πŸ›‘οΈ Safety Summary

Very low mammalian toxicity at application rates. Skin tingling (paresthesia) on contact β€” transient, not a sign of systemic toxicity. Wear gloves and avoid inhaling dust during application. Respiratory protection (N95) recommended when dusting in enclosed spaces. Toxic to cats β€” ensure dry before cat access.

Example
0.5 oz
per gallon
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πŸ”¬ Resistance Status

Resistance documented in German cockroaches and bed bugs β€” similar profile to other pyrethroids. Delta Dust is still highly effective for ants, yellow jackets, cluster flies, stink bugs, and most other target pests in wall voids.

🏷️ Common Products Containing Deltamethrin

Delta DustSuspend SCSuspend PolyzoneCyzmic CS

πŸ› Pests This Treats β€” Learn More

Click any pest to view its full identification guide, biology, and treatment options.

πŸ› Ants β†’ πŸ› Bed Bug β†’ πŸ› Cluster Flies β†’ πŸ› Cockroaches β†’ πŸ› Flies β†’ πŸ› Scales β†’ πŸ› Stink Bug β†’ πŸ› Ticks β†’ πŸ› Yellow Jacket β†’

🌿 Environmental & Ecological Impact

🐝 Bees / PollinatorsHIGH
🐟 Fish / Aquatic LifeVERY HIGH
🐦 BirdsLOW
πŸ• Mammals / PetsLOW
🦐 Aquatic InvertebratesVERY HIGH
πŸ’‘ Very toxic to aquatic life. Low mammalian toxicity but high insect toxicity.

πŸ”„ Alternatives & Related Products

Same chemical class or different approaches to the same pests.

πŸ”„
Bifenthrin
Same class: Synthetic Pyrethroid
πŸ”„
Permethrin
Same class: Synthetic Pyrethroid
πŸ”„
Cypermethrin
Same class: Synthetic Pyrethroid
↔️
Pyrethrin
Different approach: Botanical Pyrethrin
↔️
Boric Acid
Different approach: Inorganic

❓ Frequently Asked Questions

Q: Is deltamethrin safe for pets?
Follow the product label. Keep pets out of treated areas until completely dried (2–4 hours for sprays). Once dry, treated surfaces pose minimal risk to dogs and cats.
Q: Can I use deltamethrin indoors?
Check the specific product label β€” formulations vary. Baits and dusts often have indoor labeling; concentrates and granulars are typically outdoor.
Q: How long does deltamethrin last after application?
Residual varies by formulation, surface type, weather, and UV exposure. Indoor applications last longer than outdoor. Check the product label for re-application intervals.
Q: What should I do if exposed?
Remove contaminated clothing, wash skin with soap and water. For eye contact, rinse 15–20 minutes. For ingestion or severe symptoms, call Poison Control (1-800-222-1222). Have the product label available.

πŸ“‹ Safety Data Sheet (SDS)

πŸ“‹

Deltamethrin β€” Safety Data Sheet

View the official SDS document for this product directly on the CDMS label database.

Deltamethrin Safety Data Sheet page 1
πŸ“„ Deltamethrin β€” Safety Data Sheet Β· View the complete SDS document above or download below
πŸ“š Sources: EPA Pesticide Labels Β· NPIC Pesticide Info
Published: Jan 1, 2025 Β· Updated: Apr 7, 2026
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Reviewed by Derek GiordanoContent reviewed by a licensed pest management professional and cross-referenced against EPA, university extension, and manufacturer technical data. Last reviewed: April 2026.