Active ingredient profile

Hexythiazox

IRAC Group 10A mite growth inhibitors affecting CHS1, a growth-regulation mode of action shared with clofentezine.[2]

Hexythiazox is a mite growth inhibitor in IRAC Group 10A. Hexygon IQ, registered as Hexygon EW, is a commercial-use emulsion that controls spider mite eggs and immature mites on ornamentals, turf, Christmas trees and home fruit and nut trees.[1][2]

The label is the law. Rates and restrictions below are taken from the product labels listed under Sources. Your product's own label governs; read it before you mix or apply. Mixing calculator · Disclaimer

Active ingredient
Hexythiazox
Chemical class
IRAC Group 10A mite growth inhibitors affecting CHS1, a growth-regulation mode of action shared with clofentezine.[2]
Mode of action
IRAC Group 10A: Mite growth inhibitors affecting CHS1: clofentezine, diflovidazin, hexythiazox[2][1]
Signal word
Hexygon IQ Miticide (registered as Hexygon EW Miticide): Caution[1]

Who can apply it at home

The label allows use in home plantings, ornamental landscaping and residential lawns, but only by licensed commercial pesticide applicators. It isn't a do-it-yourself product.[1]

Residential apples and pears need 28 days between spraying and harvest, and home stone fruit and nut trees need 7 days. The lawn uses exclude California.[1]

Rotation and cross-resistance

IRAC groups hexythiazox with clofentezine because mites resistant to one show cross-resistance to the other, even though the chemicals differ in structure.[2]

To slow resistance, the label says to rotate to a miticide from a different group rather than repeating Group 10A sprays.[1]

Where it is used

Spray at the first sign of mites, before adults build up. It kills eggs and young mites but leaves adult spider mites alive.[1]

Adults that touch treated leaves lay eggs that won't hatch. With many adults already present, the label suggests pairing it with a contact adulticide.[1]

Only one application of this or any other hexythiazox product per crop per year is allowed, so time it well.[1]

Get thorough, uniform coverage of all plant surfaces. Emulsions can spot leaves in hot weather or slow drying, so avoid excess runoff.[1]

Products and registrations

ProductRegistrantEPA Reg. No.Active %FormulationSignal word
Hexygon IQ Miticide (registered as Hexygon EW Miticide)[1]Gowan Company, LLC10163-36511.93%emulsion in waterCaution

Label rates

ProductUsePestsRate
Hexygon IQ Miticide (registered as Hexygon EW Miticide)Ornamentals, nonbearing fruit trees and vines, landscape plantings, lawns and turf, Christmas trees, and residential apple, pear, peach, plum and nut treesTwo-spotted, Pacific, spruce, southern red, European red, strawberry and other spider mites; clover, Banks grass and brown wheat mites on turf4–8 oz product per 100 gallons of water[1]
The per-acre equivalent is 12 to 24 ounces. Use the higher end for heavier infestations or big, dense trees, and never go below the labeled rate.
Hexygon IQ Miticide (registered as Hexygon EW Miticide)Ornamental plants, lawns and turf, orchids, greenhouse tomatoes and peppers, measured by areaSpider mites listed on the label0.28–0.55 oz product per 1,000 sq ft[1]
Use enough water for complete coverage of every plant surface. On turf, spray at the first signs of mite egg laying.

Safety and environmental hazards

People

Signal word CAUTION: harmful if swallowed, inhaled or absorbed through skin, and causes moderate eye irritation. Handlers wear long sleeves, long pants, chemical-resistant gloves, shoes and socks. It contains petroleum distillate.[1]

Pets

For landscape and other non-farm uses, the label says to keep children, pets and unprotected people out of treated areas until the spray has dried.[1]

Bees and pollinators

The label carries no bee or pollinator warning.[1]

Fish and water

Toxic to fish and aquatic invertebrates. Never spray it onto water, and keep drift and runoff out of nearby ponds and streams.[1]

Common questions

Does hexythiazox kill adult spider mites?
No. The label says adults aren't directly affected, though eggs laid by treated females won't hatch. It works on eggs and immature mites.[1]
How much Hexygon IQ per 100 gallons?
4 to 8 ounces per 100 gallons of water, or 12 to 24 ounces per acre, applied once a year.[1]
Can I spray Hexygon on my lawn?
Lawns and turf are on the label outside California, but home lawns and landscapes must be treated by a licensed commercial applicator.[1]

Sources

  1. U.S. EPA Pesticide Product Label System, “Hexygon EW Miticide label, EPA Reg. No. 10163-365 (EPA-stamped, Nov. 13, 2018).” www3.epa.gov/pesticides/chem_search/ppls/010163-00365-20181113.pdf (accessed 2026-10-06)
  2. Insecticide Resistance Action Committee, “IRAC Mode of Action Classification Scheme, Version 11.5 (Feb. 2026).” irac-online.org/documents/moa-classification/ (accessed 2026-10-06)

Updated 2026-10-06. Built from sourced records; every rate traces to a product label. Spot an error? Tell us.