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Active ingredient profile

Sulfoxaflor

Sulfoximine; IRAC Group 4C nicotinic acetylcholine receptor competitive modulators.[2]

Sulfoxaflor is a sulfoximine insecticide (IRAC Group 4C). It acts on the same nerve receptor as neonicotinoids but sits in a separate subgroup. Transform WG is an agricultural product for sucking insects such as aphids, whiteflies, plant bugs and stink bugs on a long list of crops.[1][2]

The label is the law. Read your product's label before you mix or apply; the rates here come from the labels listed under Sources.

Active ingredient
Sulfoxaflor (CAS 946578-00-3)
Chemical class
Sulfoximine; IRAC Group 4C nicotinic acetylcholine receptor competitive modulators.[2]
Mode of action
IRAC Group 4C: Nicotinic acetylcholine receptor (nAChR) competitive modulators: sulfoximines[2]
Signal word
Transform WG Insecticide: Danger[1]

A separate group from neonicotinoids

IRAC puts sulfoximines in Group 4C, distinct from the 4A neonicotinoids such as imidacloprid, acetamiprid and clothianidin, though both act on the nicotinic acetylcholine receptor.[2]

Where it is used

Many crop sections forbid applying it from 3 days before bloom until after petal fall; other crops allow only one application in that window per year.[1]

Treat according to local economic thresholds, using the higher rate for heavy populations; whiteflies may need two applications.[1]

Labeled crops include vegetables, fruits, berries, citrus, cotton, soybeans, grains and many more, each with its own harvest interval.[1]

Products and registrations

ProductRegistrantEPA Reg. No.Active %FormulationSignal word
Transform WG Insecticide[1]Corteva Agriscience, LLC62719-62550.0%water-dispersible granuleDanger

Label rates

ProductUsePestsRate
Transform WG InsecticideBroccoli, Brussels sprouts, cabbage, cauliflower and kohlrabi (one of many labeled crops)Aphids; silverleaf and sweetpotato whiteflies; thrips (suppression)0.75–2.75 oz product per acre[1]
0.75 to 1.0 oz per acre for aphids and 2.0 to 2.75 oz for whiteflies. No application within 3 days of harvest, at least 7 days apart, no more than four per crop, and no more than 8.5 oz per acre per year.

Safety and environmental hazards

People

Signal word DANGER: the product is corrosive, causes irreversible eye damage and is harmful if swallowed.[1]

Pets

Hazard statements cover people and domestic animals; it is an agricultural product used under the Worker Protection Standard, not around homes.[1]

Bees and pollinators

Highly toxic to bees and other pollinators exposed to direct treatment or residues on blooming crops or weeds. The label reports an RT25 of 3 hours or less, the time field-weathered residues stay toxic to honey bees.[1]

Fish and water

Do not apply directly to water or where surface water is present, and don't contaminate water when disposing of washwater.[1]

Common questions

Is sulfoxaflor a neonicotinoid?
Not by IRAC's classification. It is a sulfoximine in Group 4C; neonicotinoids are Group 4A. Both act on the same receptor.[2]
Why does Transform WG say DANGER?
The concentrate is corrosive and causes irreversible eye damage, which earns the DANGER signal word.[1]
Can sulfoxaflor be sprayed during bloom?
For many crops, no: the label bars application from 3 days before bloom until after petal fall.[1]

Sources

  1. U.S. EPA Pesticide Product Label System, “Transform WG Insecticide label, EPA Reg. No. 62719-625 (EPA-stamped, Jan. 8, 2021).” www3.epa.gov/pesticides/chem_search/ppls/062719-00625-20210108.pdf (accessed 2026-10-06)
  2. Insecticide Resistance Action Committee, “IRAC Mode of Action Classification Scheme, Version 11.5 (Feb. 2026).” irac-online.org/documents/moa-classification/ (accessed 2026-10-06)

Updated 2026-10-06. Built from sourced records; every rate traces to a product label. Spot an error? Tell us.