Active ingredient profile

Spirotetramat

Tetronic and tetramic acid derivatives; IRAC Group 23 inhibitors of acetyl-CoA carboxylase.[2]

Spirotetramat belongs to IRAC Group 23, the tetronic and tetramic acid derivatives, which inhibits acetyl-CoA carboxylase and blocks lipid synthesis. Sold to growers as Kontos, it controls aphids, whiteflies, mealybugs, scale crawlers, mites and other sap feeders on ornamentals in greenhouses, nurseries and interiorscapes.[1][2]

The label is the law. Rates and restrictions below are taken from the product labels listed under Sources. Your product's own label governs; read it before you mix or apply. Mixing calculator · Disclaimer

Active ingredient
Spirotetramat
Chemical class
Tetronic and tetramic acid derivatives; IRAC Group 23 inhibitors of acetyl-CoA carboxylase.[2]
Mode of action
IRAC Group 23: Inhibitors of acetyl-CoA carboxylase: tetronic and tetramic acid derivatives[2]
Signal word
Spirotetramat 240 SC Greenhouse and Nursery Insecticide/Miticide (Kontos): Caution[1]

Plants to avoid

The label does not recommend it for geraniums, orchids, hoya, Dracaena, Cordyline, Schefflera, neanthebella palm or ferns. Hydrangea, impatiens, crotons, fuchsia, petunia, peperomia, stock and cyclamen get only one application per season.[1]

Because untested varieties may react, the label says to try the rate on a small number of plants before spraying widely, including any tank mix.[1]

Resistance and rotation

The label says Group 23 studies have shown no cross-resistance with other chemical classes. It still urges a block or windowed rotation with other modes of action before more Group 23 sprays on the same pest.[1]

Where it is used

After a foliar spray it is fully systemic, moving through both phloem and xylem into new shoots, leaves and roots. Insects mostly take it in by feeding, and treated adults may lay fewer eggs.[1]

Start sprays before pest numbers build or when damage is first noticed. A spreader-sticker or penetrating adjuvant may improve uptake into leaves.[1]

Mites and thrips need an early start: heavy existing mite populations won't be controlled, and only immature thrips on foliage are controlled, with thrips in buds merely suppressed.[1]

For container drenches, use just enough water to wet the potting mix without it running out the bottom, then irrigate carefully for the next 10 days.[1]

Products and registrations

ProductRegistrantEPA Reg. No.Active %FormulationSignal word
Spirotetramat 240 SC Greenhouse and Nursery Insecticide/Miticide (Kontos)[1]Environmental Science U.S., LLC (Envu)101563-13022.4%suspension concentrateCaution

Label rates

ProductUsePestsRate
Spirotetramat 240 SC Greenhouse and Nursery Insecticide/Miticide (Kontos)Flowers, foliage plants, groundcovers, shrubs, evergreens and trees (including non-bearing fruit and nut trees) in and around greenhouses and nurseriesAdelgids, aphids, leafhoppers, mealybugs, psyllids, scale crawlers, spider and tarsonemid mites, spittlebugs, thrips, whiteflies1.7–3.4 fl oz product per 100 gallons of water[1]
That is 1.5 to 3.0 mL per 3 gallons of water. Reapply at 14- to 28-day intervals if needed. No more than 25 fl oz per acre per season, and no more than 5.1 fl oz per acre in one application on outdoor ornamentals.

Safety and environmental hazards

People

Signal word CAUTION: harmful if swallowed or absorbed through skin, and causes moderate eye irritation. Prolonged or repeated skin contact may cause allergic reactions; handlers wear eyewear and chemical-resistant gloves, and the re-entry interval is 24 hours.[1]

Pets

The label's hazard statement covers humans and domestic animals alike: harmful if swallowed or absorbed through skin. It is a greenhouse, nursery and interiorscape product, not one for home use around pets.[1]

Bees and pollinators

Potentially toxic to honey bee larvae through residues in pollen and nectar, though not to adult bees. Adults that contact spray or residues on blooming plants can carry it back to the larvae.[1]

Fish and water

Toxic to aquatic invertebrates and oysters, with a high potential for runoff for several weeks after application. It can also reach groundwater in permeable soils with a shallow water table.[1]

Common questions

How much Kontos per gallon?
The label gives 1.5 to 3.0 mL of product per 3 gallons of water, which is the same as 1.7 to 3.4 fl oz per 100 gallons.[1]
Is spirotetramat systemic?
Yes. The label calls it fully systemic, moving through phloem and xylem to new shoots, leaves and roots after a foliar spray.[1]
Is spirotetramat harmful to bees?
The label says it can harm honey bee larvae through residues in pollen and nectar, but it is not toxic to adult honey bees.[1]

Sources

  1. U.S. EPA Pesticide Product Label System, “Spirotetramat 240 SC Greenhouse and Nursery Insecticide/Miticide (Kontos) label, EPA Reg. No. 101563-130 (EPA-stamped, Nov. 13, 2025).” www3.epa.gov/pesticides/chem_search/ppls/101563-00130-20251113.pdf (accessed 2026-10-06)
  2. Insecticide Resistance Action Committee, “IRAC Mode of Action Classification Scheme, Version 11.5 (Feb. 2026).” irac-online.org/documents/moa-classification/ (accessed 2026-10-06)

Updated 2026-10-06. Built from sourced records; every rate traces to a product label. Spot an error? Tell us.